一种与HLA-DR9、DQ9（DQA1*0302）相关的新型TaqI/DQA限制性片段长度多态性。
A novel TaqI/DQA RFLP associated with HLA-DR9, DQ9 (DQA1*0302).
作者信息
Vilches C, de Pablo R, Solís R, Martín R, Herrero M J, Moreno M E, Kreisler M
机构信息
Servicio de Immunología, Hospital Puerto de Hierro, Madrid, Spain.
出版信息
Eur J Immunogenet. 1995 Jun;22(3):261-4. doi: 10.1111/j.1744-313x.1995.tb00240.x.
A new TaqI/DQA restriction fragment length polymorphism (RFLP) has been found in two Spanish Caucasoid individuals. The novel polymorphic fragment has a relative mobility of 4.2 kb and is associated with an HLA-A2,Cw1401,B51,DR9,DR53,DQ9 haplotype. Nucleotide sequence analysis indicates that individuals showing this RFLP pattern do not carry a new DQA1 allele, but that (DQA10302) commonly observed in DR9,DQ9 haplotypes. The new RFLP seems to be a locally restricted marker of uncertain origin.
在两名西班牙高加索人中发现了一种新的TaqI/DQA限制性片段长度多态性（RFLP）。这种新的多态性片段的相对迁移率为4.2 kb，与HLA-A2、Cw1401、B51、DR9、DR53、DQ9单倍型相关。核苷酸序列分析表明，表现出这种RFLP模式的个体并不携带新的DQA1等位基因，而是携带DR9、DQ9单倍型中常见的（DQA10302）。这种新的RFLP似乎是一种来源不明的局部限制性标记。
Zotero 插件