Chen M Y, Donofrio P D, Frederick M G, Ott D J, Pikna L A
Department of Radiology, Bowman Gray School of Medicine of Wake Forest University, Winston-Salem, North Carolina, USA.
Dysphagia. 1996 Winter;11(1):11-3. doi: 10.1007/BF00385793.
We reviewed 14 patients with clinically confirmed Guillain-Barré syndrome for swallowing dysfunction. All had swallowing dysfunction varying from mild to severe. Six patients (43%) had equivalent impairment during oral and pharyngeal phases. Seven patients (50%) had more severe functional abnormalities during the pharyngeal phase than during the oral phase. One patient (7%) had moderate disorder during the oral phase and mild disorder during the pharyngeal phase. Thirty-six percent of the patients had moderate-to-severe dysfunction during the oral phase, and 71% had moderate-to-severe dysfunction during the pharyngeal phase. In 5 patients who had multiple sequential examinations, moderate or severe swallowing disorders improved to mild-to-moderate disorders within 4-8 weeks after the onset of the symptoms. Residual swallowing disorders may be seen in those who had severe swallowing dysfunction during the later phases of their disease. Further investigations are needed to determine if swallowing abnormalities persist after complete recovery from Guillain-Barré syndrome.
我们对14例临床确诊为吉兰-巴雷综合征的患者进行了吞咽功能障碍评估。所有患者均有不同程度的吞咽功能障碍,从轻度到重度不等。6例患者(43%)口腔期和咽期功能受损程度相当。7例患者(50%)咽期的功能异常比口腔期更为严重。1例患者(7%)口腔期为中度功能障碍,咽期为轻度功能障碍。36%的患者口腔期有中度至重度功能障碍,71%的患者咽期有中度至重度功能障碍。在5例接受多次连续检查的患者中,中度或重度吞咽障碍在症状出现后4 - 8周内改善为轻度至中度障碍。疾病后期有严重吞咽功能障碍的患者可能会出现残留吞咽障碍。需要进一步研究以确定吉兰-巴雷综合征完全康复后吞咽异常是否持续存在。