Mehlhorn H, Lelandais M, Korth H G, Foyer C H
Institut für Angewandte Botanik, Universität-GH-Essen, Germany.
FEBS Lett. 1996 Jan 15;378(3):203-6. doi: 10.1016/0014-5793(95)01448-9.
Ascorbate-dependent detoxification of hydrogen peroxide by guaiacol-type peroxidases is increased considerably in the presence of 3,4-dihydroxyphenolic compounds, suggesting that ascorbate is the natural substrate for many types of peroxidase in situ and not just the ascorbate-specific peroxidases. The ascorbate-dependent destruction of hydrogen peroxide in the more acidic cellular compartments such as the vacuole may be an important function of such non-specific peroxidases. The stress-induced production of phenolic compounds would render the guaiacol peroxidases in other less acidic-cellular sites effective as ascorbate-dependent H2O2-detoxifying enzymes.
在愈创木酚型过氧化物酶作用下，抗坏血酸对过氧化氢的解毒作用在3,4 - 二羟基酚类化合物存在时会显著增强，这表明抗坏血酸是许多类型过氧化物酶在原位的天然底物，而不仅仅是抗坏血酸特异性过氧化物酶的底物。在如液泡等酸性更强的细胞区室中，抗坏血酸依赖的过氧化氢破坏作用可能是此类非特异性过氧化物酶的重要功能。应激诱导产生的酚类化合物会使其他酸性较弱的细胞部位的愈创木酚过氧化物酶作为依赖抗坏血酸的H2O2解毒酶发挥作用。
