Aspillaga C, Vial M T
Departamento y Servicio de Obstetricia y Ginecología, Hospital San Borja-Arriarán, Universidad de Chile.
Rev Chil Obstet Ginecol. 1995;60(2):131-4.
Premature amnion rupture occurs in about 5%-7% of normal pregnancies. Early and prolonged decreased amount of amniotic fluid determines deformities and impairment of fetal lung development. We report a case of a 35 year old mother with severe oligohydramnios since 25 weeks gestation, secondary to premature rupture of membranes. A male baby was born a 31 weeks with unmanageable asphyxia dying eleven hours later. Pathologic findings revealed a Potter phenotype including severe lung hypoplasia. The fall in intrauterine volume affects, through diverse mechanisms lung growth and maturation. The duration and severity of oligohydramnios are important elements in predicting the risk of pulmonary hypoplasia and neonatal morbidity.
胎膜早破发生于约5%-7%的正常妊娠中。羊水过少出现过早且持续时间长会导致胎儿肺部发育畸形和受损。我们报告一例35岁母亲的病例，自妊娠25周起出现严重羊水过少，继发于胎膜早破。一名男婴于31周出生，出生时窒息难以处理，11小时后死亡。病理检查结果显示为波特综合征，包括严重肺发育不全。子宫内体积的减少通过多种机制影响肺的生长和成熟。羊水过少的持续时间和严重程度是预测肺发育不全风险和新生儿发病率的重要因素。
