[A study of the influence of sutures and tension on skin cicatrization in loss of substance in 18 minipigs].

This study concerned the evaluation of wound healing after extensive skin resections in 18 minipigs, sutured with: continuous intradermal Polyglactin 910 suture or Polyamide, an interrupted intradermal sutures using the same resorbable suture material. Three equivalent groups were studied: 0, 3 and 6 cm skin resections were studied after using a dynamometer to record the tension necessary to join the wound margins. Results were evaluated 1 month later by light and electron microscopy, and were statistically correlated by Pearson's test. The wound tension was correlated with skin resection (r = 0.97, p < 10-4). The scar width was exponentially correlated with tension (r = 0.70, p < 10-3); the fibrous and cellular appearances increased with the skin resection. The absence of any significant statistical results prevents any conclusion concerning the superiority of one suture material or suture technique, but the group with no resection led to homogenous results, regardless of the suture technique, or suture material used. 3 and 6 cm resection the groups led to unpredictable and various results. Granulous reactions were observed in 7 out of 12 cases with resorbable suture, and only 1 of the 8 cases with non resorbable suture, but these results are not significant.