Engels E, Marks P W, Kazanjian P
Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.
Clin Infect Dis. 1995 Aug;21(2):427-8. doi: 10.1093/clinids/21.2.427.
The diagnostic usefulness of 69 bone marrow examinations (BMEs) performed for evaluating unexplained fever in 65 persons who were infected with human immunodeficiency virus was retrospectively compared with the usefulness of other diagnostic modalities used to investigate the cause of fever. An etiology for the fever was identified by BME in 22 of the 69 cases (diagnostic yield, 32%). In 19 of these 22 cases, the same diagnosis had been made by another diagnostic modality, but the diagnosis was made by BME as rapidly or sooner in 10 of the 19 cases and was made exclusively by BME in the three other cases. We suggest that BME is indicated when a diagnosis is urgently sought or when an evaluation with other diagnostic modalities has been unsuccessful.
对65例感染人类免疫缺陷病毒的患者进行了69次骨髓检查（BME）以评估不明原因发热，回顾性比较了BME与用于调查发热原因的其他诊断方法的有效性。69例病例中，有22例（诊断率32%）通过BME确定了发热病因。在这22例中的19例中，另一种诊断方法也做出了相同诊断，但在这19例中的10例中，BME做出诊断的速度相同或更快，另外3例则完全是由BME做出诊断。我们建议，当急需做出诊断或其他诊断方法评估未成功时，应进行BME。
