作为生物活性陶瓷骨水泥植入兔股骨的羟基磷灰石热分解产物的抗压强度和骨结合强度

Compressive and bone-bonding strength of hydroxyapatite thermal decomposition product implanted in the femur of rabbit as a bioactive ceramic bone cement.

作者信息

Takahashi A, Koshino T

机构信息

Department of Orthopaedic Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.

出版信息

Biomaterials. 1995 Aug;16(12):937-43. doi: 10.1016/0142-9612(95)93119-x.

DOI:10.1016/0142-9612(95)93119-x

PMID:8562783

Abstract

Hydroxyapatite thermal decomposition product (HATDP) after mixing with water was injected into the femur of rabbits, and its biocompatibility, compressive strength and bone-bonding strength were investigated. The compressive strength of a block of HATDP was 56.0 MPa 4 weeks after injection, which was about 60% of that of poly(methyl methacrylate) (PMMA) cement. The bone-bonding strength was 8.2 MPa 4 weeks after injection, which was significantly higher than that of PMMA cement. HATDP seems to be useful as a cement material because of its good bone-bonding property and relatively high mechanical strength.

摘要

将羟基磷灰石热分解产物（HATDP）与水混合后注入兔股骨，研究其生物相容性、抗压强度和骨结合强度。注射4周后，一块HATDP的抗压强度为56.0MPa，约为聚甲基丙烯酸甲酯（PMMA）骨水泥抗压强度的60%。注射4周后，骨结合强度为8.2MPa，明显高于PMMA骨水泥。由于HATDP具有良好的骨结合性能和相对较高的机械强度，它似乎可作为一种骨水泥材料。