Takahashi A, Koshino T
Department of Orthopaedic Surgery, Yokohama City University School of Medicine, Kanagawa, Japan.
Biomaterials. 1995 Aug;16(12):937-43. doi: 10.1016/0142-9612(95)93119-x.
Hydroxyapatite thermal decomposition product (HATDP) after mixing with water was injected into the femur of rabbits, and its biocompatibility, compressive strength and bone-bonding strength were investigated. The compressive strength of a block of HATDP was 56.0 MPa 4 weeks after injection, which was about 60% of that of poly(methyl methacrylate) (PMMA) cement. The bone-bonding strength was 8.2 MPa 4 weeks after injection, which was significantly higher than that of PMMA cement. HATDP seems to be useful as a cement material because of its good bone-bonding property and relatively high mechanical strength.
将羟基磷灰石热分解产物（HATDP）与水混合后注入兔股骨，研究其生物相容性、抗压强度和骨结合强度。注射4周后，一块HATDP的抗压强度为56.0MPa，约为聚甲基丙烯酸甲酯（PMMA）骨水泥抗压强度的60%。注射4周后，骨结合强度为8.2MPa，明显高于PMMA骨水泥。由于HATDP具有良好的骨结合性能和相对较高的机械强度，它似乎可作为一种骨水泥材料。
