Hardoff R, Baron E, Sheinfeld M, Luboshitsky R
Department of Nuclear Medicine, Carmel Medical Center, Haifa, Israel.
Clin Nucl Med. 1995 Nov;20(11):981-4. doi: 10.1097/00003072-199511000-00008.
Eleven patients, each with a painful solitary cold nodule of the thyroid were evaluated. All patients had subacute thyroiditis associated with neck pain and tenderness. Despite elevated sedimentation rate and increased thyroglobulin levels, nine of the patients were euthyroid, and I-131 uptake was normal in six. In all patients, thyroid scintigraphy demonstrated a solitary cold nodule that resolved regardless of anti-inflammatory therapy. Granulomatous subacute thyroiditis is characterized by decreased I-131 uptake accompanied by transient hyperthyroidism. The uncommon localized variant of this entity may present with a painful solitary nodule, normal or only moderately decreased I-131 uptake, and should be suspected even in euthyroid patients.
对11例甲状腺有单个疼痛性冷结节的患者进行了评估。所有患者均患有亚急性甲状腺炎，并伴有颈部疼痛和压痛。尽管血沉升高和甲状腺球蛋白水平升高，但9例患者甲状腺功能正常，6例患者的碘-131摄取正常。所有患者的甲状腺闪烁显像均显示单个冷结节，无论抗炎治疗如何，该结节均会消退。肉芽肿性亚急性甲状腺炎的特征是碘-131摄取减少并伴有短暂性甲状腺功能亢进。这种疾病罕见的局限性变体可能表现为单个疼痛性结节，碘-131摄取正常或仅中度降低，即使在甲状腺功能正常的患者中也应怀疑。
