Kaplan V, Bingisser R, Li Y, Hess T, Russi E W, Bloch K E
Departement für Innere Medizin, Universitätsspital Zürich.
Schweiz Med Wochenschr. 1996 Jan 9;126(1-2):15-21.
Continuous positive airway pressure (CPAP) is the treatment of first choice for obstructive sleep apnea syndrome (OSAS). The effect of this treatment is highly dependent on patient compliance. To identify factors associated with compliance, a questionnaire was sent to 53 patients with OSAS for whom CPAP treatment had been prescribed. Response rate was 96%. 45 of 51 patients (88%) stated they had been on CPAP for a period of 30 to 2340 (median 292) days. 43 of the 51 patients (84%) who used CPAP regularly, defined as at least 4 hours nightly on 5 nights per week, were considered as compliant with the prescribed treatment. They did not differ from non-compliant patients either in initial symptom score or in apnea/hypopnea index at initial presentation. The most consistent factor associated with compliance was symptomatic improvement with CPAP. Side effects were more common in non-compliant patients. Symptomatic improvement during an initial trial with CPAP should be considered when starting definitive treatment, in order to optimize compliance.
持续气道正压通气（CPAP）是阻塞性睡眠呼吸暂停综合征（OSAS）的首选治疗方法。这种治疗效果高度依赖于患者的依从性。为了确定与依从性相关的因素，向53名已开具CPAP治疗处方的OSAS患者发送了一份问卷。回复率为96%。51名患者中有45名（88%）表示他们使用CPAP的时间为30至2340天（中位数为292天）。51名定期使用CPAP（定义为每周5晚每晚至少使用4小时）的患者中有43名（84%）被认为依从规定治疗。他们在初始症状评分或初次就诊时的呼吸暂停/低通气指数方面与不依从的患者没有差异。与依从性最一致相关的因素是CPAP治疗后症状改善。副作用在不依从的患者中更常见。开始确定性治疗时，应考虑在CPAP初始试验期间的症状改善情况，以优化依从性。
