东欧和东南欧的乙肝表面抗原亚型
Subtypes of HBsAg in eastern and south-eastern Europe.
作者信息
Madaliński K, Holland P V, Moraczewska Z, Kalinowska B, Alter H J
出版信息
Vox Sang. 1977;32(4):224-9. doi: 10.1111/j.1423-0410.1977.tb00634.x.
A total of 481 serum samples was collected from asymptomatic carriers of HBSAg as well as some patients with acute and chronic hepatitis, type B. The sera were obtained mainly from blood banks in the following countries: Poland, Hungary, Romania, Bulgaria, Yugoslavia, and the European part of the Soviet Union. Asymptomatic carriers of HBsAg from Poland and Hungary showed a preponderance of adw subtype over ayw subtype (Poland -80.7% adw, Hungary -72.2% adw). Carriers from the remaining countries showed the reverse situation: Bulgaria -71.5% ayw, Yugoslavia -79.0% ayw, Romania -82.8% ayw, Soviet Union -87.5% ayw. No individuals were found among these indigenous populations to have the adr or ayr subtypes but two carriers appeared to have the unusual subtype adyw.
共采集了481份血清样本，这些样本来自乙肝表面抗原（HBsAg）无症状携带者以及一些急慢性乙型肝炎患者。血清主要取自以下国家的血库：波兰、匈牙利、罗马尼亚、保加利亚、南斯拉夫以及苏联的欧洲部分地区。来自波兰和匈牙利的HBsAg无症状携带者中，adw亚型占比高于ayw亚型（波兰——80.7%为adw，匈牙利——72.2%为adw）。其余国家的携带者情况则相反：保加利亚——71.5%为ayw，南斯拉夫——79.0%为ayw，罗马尼亚——82.8%为ayw，苏联——87.5%为ayw。在这些本地人群中未发现携带adr或ayr亚型的个体，但有两名携带者似乎携带罕见的adyw亚型。
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