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在小家鼠栗色亚种中发现的位于粉红眼稀释(p)位点的一个新的自发等位基因。

A new spontaneous allele at the pink-eyed dilution (p) locus discovered in Mus musculus castaneus.

作者信息

Tsuji A, Wakayama T, Ishikawa A

机构信息

Laboratory of Animal Genetics, School of Agricultural Sciences, Nagoya University, Aichi, Japan.

出版信息

Exp Anim. 1995 Oct;44(4):347-51. doi: 10.1538/expanim.44.347.

Abstract

Mutant mice characterized by a cream coat and pink eyes were spontaneously discovered among the descendants of Indonesian wild mice (Mus musculus castaneus). This mutant phenotype was controlled by a single autosomal recessive gene that was allelic to the pink-eyed dilution (p) gene. The mutant mouse phenotypically resembled the original p mouse which was the first mutant identified at this locus. Nevertheless, these two alleles differed in origin, a previous report suggesting that the original p allele was derived from Japanese wild mice (M. m. molossinus). Thus the symbol pcas (pink-eyed castaneus) was proposed for the present mutation allele.

摘要

在印度尼西亚野生小鼠(小家鼠栗色亚种)的后代中,自发发现了具有奶油色皮毛和粉红色眼睛特征的突变小鼠。这种突变表型由一个常染色体隐性基因控制,该基因与粉红眼稀释(p)基因等位。突变小鼠在表型上类似于最初在该位点鉴定出的第一个突变体——原始的p小鼠。然而,这两个等位基因的起源不同,先前的一份报告表明原始的p等位基因源自日本野生小鼠(小家鼠小家鼠亚种)。因此,为当前的突变等位基因提议使用符号pcas(粉红眼栗色)。

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