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[人粪便、肠黏膜及胆汁中的碱性磷酸酶以及粪便中5'-核苷酸酶的出现(作者译)]

[Alkaline phosphatases in human feces, intestinal mucosa and bile, and the occurrence of 5'-nucleotidase in feces (author's transl)].

作者信息

Benić V, Fiser-Herman M

出版信息

Z Klin Chem Klin Biochem. 1975 Oct;13(10):437-44.

PMID:858
Abstract

Alkaline phosphatase (EC 3.1.3.1) in extracts of human feces resembles alkaline phosphatase in extracts of duodenal mucosa, except for its electrophoretic mobility in starch gel. It is very probable that the normal feces alkaline phosphatase derives from intestinal mucosa. Gall bladder alkaline phosphatase, which is markedly different, has not been found in normal feces. Some patients with acute viral hepatitis or protozoasis excrete an alkaline phosphatase which resembles gall bladder alkaline phosphatase and has the characteristics of 5'-nucleotidase (EC 3.1.3.5). The appearance of this enzyme correlates with low total alkaline phosphatase activity of the excreta.

摘要

人粪便提取物中的碱性磷酸酶(EC 3.1.3.1)与十二指肠黏膜提取物中的碱性磷酸酶相似,只是其在淀粉凝胶中的电泳迁移率有所不同。正常粪便碱性磷酸酶很可能来源于肠黏膜。在正常粪便中未发现明显不同的胆囊碱性磷酸酶。一些急性病毒性肝炎或原虫病患者排出的碱性磷酸酶与胆囊碱性磷酸酶相似,并具有5'-核苷酸酶(EC 3.1.3.5)的特性。这种酶的出现与排泄物中总碱性磷酸酶活性降低相关。

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引用本文的文献

1
5'-Nucleotidase activities in sera and liver tissues of viral hepatitis patients.
Gastroenterol Jpn. 1990 Apr;25(2):199-205. doi: 10.1007/BF02776816.

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