L-赖氨酸给药对断奶大鼠抗坏血酸代谢某些方面的影响。
Effects of L-lysine administration on certain aspects of ascorbic acid metabolism in weanling rats.
作者信息
Chatterjee A K, Basu J, Datta S C, Sen Gupta K, Ghosh B B
出版信息
Experientia. 1977 Mar 15;33(3):291-2. doi: 10.1007/BF02002785.
PMID:858347
Abstract
L-lysine administration to male weanling rats at a dose of 110.4 mg (25% LD50) per 100 g body weight per day for 15 days reduced the liver total ascorbic acid level. The biosynthesis as well as the degradation of L-ascorbic acid was diminished under these conditions. The fall in liver total ascorbic acid level after L-lysine administration was ascribed to its reduced synthesis.
摘要
以每天每100克体重110.4毫克（25%的半数致死量）的剂量给雄性断奶大鼠施用L-赖氨酸，持续15天，会降低肝脏中总抗坏血酸水平。在这些条件下，L-抗坏血酸的生物合成以及降解均减少。施用L-赖氨酸后肝脏总抗坏血酸水平的下降归因于其合成减少。
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