伴有促纤维增生性成分的默克尔细胞癌。
Merkel cell carcinoma with a desmoplastic portion.
作者信息
Kossard S, Wittal R, Killingsworth M
机构信息
Skin and Cancer Foundation, Darlinghurst, N.S.W., Australia.
出版信息
Am J Dermatopathol. 1995 Oct;17(5):517-22. doi: 10.1097/00000372-199510000-00015.
Merkel cell carcinoma of the skin usually has a trabecular, intermediate-cell or small-cell pattern of differentiation. We report the case of a 66-year-old man who developed a progressive multinodular plaque that showed a prominent desmoplastic component on preliminary biopsy. Immunohistochemical and ultrastructural studies and the final surgical specimen confirmed that the tumor was a Merkel cell carcinoma. The presence of desmoplasia may mask the diagnosis of Merkel cell carcinoma.
皮肤默克尔细胞癌通常具有小梁状、中间细胞或小细胞分化模式。我们报告了一例66岁男性患者，其出现了一个进行性多结节斑块，初步活检显示有显著的促纤维增生成分。免疫组织化学和超微结构研究以及最终手术标本证实该肿瘤为默克尔细胞癌。促纤维增生的存在可能会掩盖默克尔细胞癌的诊断。
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