二肽抑制剂与嗜热菌蛋白酶结合的晶体学研究：对催化机制的启示 - Suppr

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超能文献

Crystallographic study of the binding of dipeptide inhibitors to thermolysin: implications for the mechanism of catalysis.

作者信息

Kester W R, Matthews B W

出版信息

Biochemistry. 1977 May 31;16(11):2506-16. doi: 10.1021/bi00630a030.

DOI:10.1021/bi00630a030

PMID:861218

Abstract

摘要

相似文献

Crystallographic study of the binding of dipeptide inhibitors to thermolysin: implications for the mechanism of catalysis.二肽抑制剂与嗜热菌蛋白酶结合的晶体学研究：对催化机制的启示

Biochemistry. 1977 May 31;16(11):2506-16. doi: 10.1021/bi00630a030.

Binding of N-carboxymethyl dipeptide inhibitors to thermolysin determined by X-ray crystallography: a novel class of transition-state analogues for zinc peptidases.通过X射线晶体学确定N-羧甲基二肽抑制剂与嗜热菌蛋白酶的结合：一类新型的锌肽酶过渡态类似物

Biochemistry. 1984 Nov 20;23(24):5724-9. doi: 10.1021/bi00319a010.

Structural basis for the action of thermolysin.嗜热菌蛋白酶作用的结构基础。

Matrix Suppl. 1992;1:107-11.

The binding of L-valyl-L-tryptophan to crystalline thermolysin illustrates the mode of interaction of a product of peptide hydrolysis.L-缬氨酰-L-色氨酸与结晶嗜热菌蛋白酶的结合阐明了肽水解产物的相互作用模式。

J Biol Chem. 1988 Mar 5;263(7):3256-60. doi: 10.2210/pdb3tmn/pdb.

Arazoformyl dipeptide substrates for thermolysin. Confirmation of a reverse protonation catalytic mechanism.嗜热菌蛋白酶的氮杂甲酰基二肽底物。反向质子化催化机制的确认。

Biochemistry. 1996 Jun 11;35(23):7369-77. doi: 10.1021/bi952827p.

Inhibition of thermolysin by dipeptides.

Biochemistry. 1974 Mar 12;13(6):1186-9. doi: 10.1021/bi00703a600.

Inhibition of thermolysin and neutral endopeptidase 24.11 by a novel glutaramide derivative: X-ray structure determination of the thermolysin-inhibitor complex.一种新型戊二酰胺衍生物对嗜热菌蛋白酶和中性内肽酶24.11的抑制作用：嗜热菌蛋白酶 - 抑制剂复合物的X射线晶体结构测定

Biochemistry. 1994 Jan 11;33(1):51-6. doi: 10.1021/bi00167a007.

An interactive computer graphics study of thermolysin-catalyzed peptide cleavage and inhibition by N-carboxymethyl dipeptides.嗜热菌蛋白酶催化的肽裂解以及 N-羧甲基二肽抑制作用的交互式计算机图形学研究

Biochemistry. 1984 Nov 20;23(24):5730-41. doi: 10.1021/bi00319a011.

Effect of configuration of the inhibitors on the mode of binding to the enzyme, thermolysin.

J Biomol Struct Dyn. 1984 Aug;2(1):29-40. doi: 10.1080/07391102.1984.10507544.

A crystallographic study of the complex of phosphoramidon with thermolysin. A model for the presumed catalytic transition state and for the binding of extended substances.膦甲脒与嗜热菌蛋白酶复合物的晶体学研究。推测的催化过渡态及延伸物质结合的模型。

J Mol Biol. 1977 Jul;114(1):119-32. doi: 10.1016/0022-2836(77)90286-8.

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Two thimet oligopeptidase-like Pz peptidases produced by a collagen-degrading thermophile, Geobacillus collagenovorans MO-1.由嗜热胶原降解菌嗜热栖热放线菌MO-1产生的两种类硫醚寡肽酶Pz肽酶。

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