Spivak H, Schlasinger M H, Tabanda-Lichauco R, Ferstenberg H
Department of Surgery, Beth Israel Medical Center, New York, New York, USA.
Am Surg. 1996 May;62(5):369-72.
Disseminated histoplasmosis is a rare condition that is associated with an underlying immune disorder in approximately 25 per cent of patients. It often leads to GI histoplasmosis, but when the disease predominantly affects the GI tract few, if any, pulmonary symptoms appear. Although histoplasmosis of the gastrointestinal system has been described, it rarely causes a small bowel obstruction. In fact, a recent review of the English literature revealed 77 cases of gastrointestinal histoplasmosis, with only none having clinical presentation solely involving of the jejunum and ileum in acquired immune deficiency syndrome (AIDS) patients. At the time of urgent abdominal exploration, both patients had several areas of bowel strictures with subjacent mesenteric adenopathy. They required resection of small bowel segments. Pathology examination established the diagnosis of histoplasmosis, and both patients were discharged home after antifungal therapy.
播散性组织胞浆菌病是一种罕见疾病，约25%的患者伴有潜在免疫紊乱。它常导致胃肠道组织胞浆菌病，但当疾病主要累及胃肠道时，很少（如果有的话）出现肺部症状。虽然胃肠道组织胞浆菌病已有描述，但很少引起小肠梗阻。事实上，最近对英文文献的综述显示有77例胃肠道组织胞浆菌病病例，在获得性免疫缺陷综合征（AIDS）患者中，仅有0例临床表现仅累及空肠和回肠。在紧急腹部探查时，两名患者均有多个肠段狭窄区域及相邻肠系膜淋巴结肿大。他们需要切除小肠段。病理检查确诊为组织胞浆菌病，两名患者在抗真菌治疗后出院回家。
