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用西咪替丁成功治疗的Castleman病浆细胞变异型。病例报告及文献复习。

A plasma cell variant of Castleman's disease treated successfully with cimetidine. Case report and review of the literature.

作者信息

Barbounis V, Efremidis A

机构信息

2nd Department of Medical Oncology, St. Savvas Regional Anticancer Hospital, Athens, Greece.

出版信息

Anticancer Res. 1996 Jan-Feb;16(1):545-7.

PMID:8615669
Abstract

Castleman's disease is a rare benign condition of uncertain etiology, with several forms. It is postulated that a dysregulated inflammatory response may play a role in the pathogenesis of this disease. We report on a case of Castleman's disease treated with the histamine receptor-2 antagonist cimetidine with favourable response, suggesting that cimetidine may be helpful in the treatment of this disease.

摘要

卡斯尔曼病是一种病因不明的罕见良性疾病,有多种类型。据推测,炎症反应失调可能在该疾病的发病机制中起作用。我们报告了一例用组胺H2受体拮抗剂西咪替丁治疗且反应良好的卡斯尔曼病病例,提示西咪替丁可能有助于治疗该疾病。

相似文献

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引用本文的文献

1
Castleman's disease: from basic mechanisms to molecular therapeutics.卡斯尔曼病:从基础机制到分子治疗学。
Oncologist. 2011;16(4):497-511. doi: 10.1634/theoncologist.2010-0212. Epub 2011 Mar 25.
2
Treatment of Castleman's disease.卡斯尔曼病的治疗。
Curr Treat Options Oncol. 2005 May;6(3):255-66. doi: 10.1007/s11864-005-0008-z.

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