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[假单胞菌属泌尿系统感染中的免疫调节]

[Immunomodulation in Pseudomonas urinary infection].

作者信息

Urban M, Tamele L

机构信息

Urologická klinika FN KV, Praha.

出版信息

Rozhl Chir. 1995 Nov;74(7):319-21.

PMID:8629153
Abstract

The urological department is as a rule of department with the highest incidence of nosocomial infections. They are often caused by Pseudomonas aeruginosa. In 1992 the authors started to use prophylactic immunization with antipseudomonas vaccine PSAEVA in 58 patients indicated for surgery on account of an prostate adenoma. During and after operation the incidence of Pseudomonas infection in immunized and control patients was compared. In the immunized group the incidence after operation was 1.72%, in the control group 12%. The drop of Pseudomonas infections in operated patients immunized with the anti-pseudomonas vaccine as compared with non-immunized ones was by 10.28% lower which is statistically significant--p.0.05.

摘要

泌尿外科通常是医院感染发生率最高的科室。感染常由铜绿假单胞菌引起。1992年,作者开始对58例因前列腺腺瘤而需手术的患者使用抗铜绿假单胞菌疫苗PSAEVA进行预防性免疫。在手术期间及术后,对免疫组和对照组患者铜绿假单胞菌感染的发生率进行了比较。免疫组术后感染发生率为1.72%,对照组为12%。与未免疫的手术患者相比,用抗铜绿假单胞菌疫苗免疫的手术患者铜绿假单胞菌感染率降低了10.28%,具有统计学意义(p<0.05)。

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