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[不可手术患者孤立肾肿瘤结节的超选择性栓塞术]

[Superselective embolization of tumor nodes in solitary kidney in inoperable patients].

作者信息

Sokiranski R, Görich J, van Ahlen H, Rilinger N, Vogel J, Brambs H J

机构信息

Radiologische Klinik und Poliklinik der Universität, Ulm.

出版信息

Rofo. 1996 May;164(5):427-31. doi: 10.1055/s-2007-1015683.

Abstract

PURPOSE

Evaluation of superselective embolisation of renal tumours in inoperable patients with solitary kidneys.

METHODS AND PATIENTS

Eight inoperable patients with solitary kidneys bearing tumour nodules underwent 1-3 superselective embolisation procedures with ethibloc (5x) or polyvinyl alcohol (1x). Renal function was monitored with creatinine levels. Tumour size was controlled every three months by means of sonography.

RESULTS

Technical success rate was 100%. In 3/3 patients haematuria could be stopped. Post-embolisation renal function was unchanged in 6 patients and deteriorated in two patients; creatinine level rose to a maximum of 2.2 mg%. We observed no other side effects. Seven of eight patients died during a median follow-up period of 9.3 months (4-18 months); in two cases they died due to their underlying malignant disease. One patient had local tumour progress.

CONCLUSIONS

Superselective embolisation of renal tumours in patients with solitary kidneys may be a helpful, well-tolerated therapeutic option in inoperable, symptomatic patients.

摘要

目的

评估对患有孤立肾且无法手术的患者的肾肿瘤进行超选择性栓塞治疗的效果。

方法与患者

8例患有孤立肾且有肿瘤结节的无法手术的患者接受了1 - 3次使用乙碘油(5例)或聚乙烯醇(1例)的超选择性栓塞治疗。通过肌酐水平监测肾功能。每三个月通过超声检查控制肿瘤大小。

结果

技术成功率为100%。3例患者中的血尿得以停止。栓塞后6例患者的肾功能未改变,2例患者的肾功能恶化;肌酐水平最高升至2.2mg%。未观察到其他副作用。8例患者中有7例在中位随访期9.3个月(4 - 18个月)内死亡;2例死于其潜在的恶性疾病。1例患者出现局部肿瘤进展。

结论

对于患有孤立肾的患者,肾肿瘤超选择性栓塞可能是无法手术的有症状患者的一种有益且耐受性良好的治疗选择。

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