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不带袖套或补片的聚四氟乙烯腘下动脉旁路移植术:对于没有自体静脉的患者而言,是比截肢更好的选择。

Polytetrafluoroethylene bypasses to infrapopliteal arteries without cuffs or patches: a better option than amputation in patients without autologous vein.

作者信息

Parsons R E, Suggs W D, Veith F J, Sanchez L A, Lyon R T, Marin M L, Goldsmith J, Faries P L, Wengerter K R, Schwartz M L

机构信息

Division of Vascular Surgery, Department of Surgery, Montefiore Medical Center, New York, 10467, USA.

出版信息

J Vasc Surg. 1996 Feb;23(2):347-54; discussion 355-6. doi: 10.1016/s0741-5214(96)70280-x.

Abstract

PURPOSE

This study was undertaken to evaluate our results of polytetrafluoroethylene (PTFE) tibial and peroneal artery bypasses done for limb salvage.

METHODS

Within a group of patients undergoing infrainguinal limb salvage bypasses at our institution between January 1986 and May 1995, 63 patients faced an immediate amputation, had no autologous vein on duplex examination and operative exploration, and had only a tibial or peroneal artery as an outflow vessel for bypass. Most of these patients (82%) had two or more prior ipsilateral infrainguinal bypasses. These 63 patients underwent 66 PTFE bypasses to a tibial or peroneal artery without a distal anastomotic vein cuff or an adjunctive arteriovenous fistula. Our results were then compared with those reported from infrapopliteal (crural) bypasses performed with alternate autologous vein sources or PTFE in conjunction with various recommended adjuncts.

RESULTS

The 3- and 5-year cumulative primary graft patency rates for our PTFE infrapopliteal bypasses were 39%+/-7% and 28%+/-9%, respectively. Secondary graft patency rates were 55%+/-8% and 43%+/-10% at 3 and 5 years, respectively. Limb salvage rates were 71%+/-7% at 3 years and 66%+/-8% at 5 years. Two-year actuarial patient survival rate was only 67%+/-7%.

CONCLUSIONS

These results indicate that a PTFE bypass to an infrapopliteal artery remains a worthwhile option in patients without usable autologous vein. The secondary patency and limb salvage rates were acceptable in this setting and were not significantly different from the best results reported with prosthetic tibial/peroneal bypasses with distal vein cuffs or patches (74% at 1 year; 58% at 3 years), arteriovenous fistulas (71% at 1 year) or composite arm vein grafts (39% and 29% at 3 and 5 years, respectively).

摘要

目的

本研究旨在评估我们采用聚四氟乙烯(PTFE)行胫动脉和腓动脉旁路移植术以挽救肢体的结果。

方法

在1986年1月至1995年5月期间,于我院接受腹股沟下肢体挽救性旁路移植术的一组患者中,63例患者面临即刻截肢,经双功超声检查和手术探查发现无自体静脉,且仅有胫动脉或腓动脉作为旁路移植的流出道血管。这些患者中的大多数(82%)先前同侧腹股沟下旁路移植术已进行过两次或更多次。这63例患者接受了66次PTFE旁路移植术,吻合至胫动脉或腓动脉,未使用远端吻合静脉袖套或辅助动静脉瘘。然后将我们的结果与采用替代自体静脉来源或PTFE并结合各种推荐辅助措施进行的腘动脉以下(小腿)旁路移植术所报告的结果进行比较。

结果

我们的PTFE腘动脉以下旁路移植术的3年和5年累积原发性移植物通畅率分别为39%±7%和28%±9%。继发性移植物通畅率在3年和5年时分别为55%±8%和43%±10%。肢体挽救率在3年时为71%±7%,在5年时为66%±8%。两年精算患者生存率仅为67%±7%。

结论

这些结果表明,对于没有可用自体静脉的患者,PTFE旁路移植至腘动脉以下动脉仍然是一个值得考虑的选择。在这种情况下,继发性通畅率和肢体挽救率是可以接受的,并且与采用带远端静脉袖套或补片的人工胫动脉/腓动脉旁路移植术(1年时为74%;3年时为58%)、动静脉瘘(1年时为71%)或复合臂静脉移植物(3年和5年时分别为39%和29%)所报告的最佳结果相比,无显著差异。

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