Hecher K, Reinhold U, Gbur K, Hackelöer B J
Abteilung für Pränatale Diagnostik und Therapie, AK Barmbek, Hamburg.
Geburtshilfe Frauenheilkd. 1996 Feb;56(2):97-100. doi: 10.1055/s-2007-1022250.
We report on the successful intrauterine surgical treatment of a twin pregnancy with an acardiac fetus. At 18 weeks of gestation the patient presented with polyhydramnios and a hydropic acardius acephalus and the donor twin showed signs of congestive heart failure. Colour Doppler ultrasound allowed localisation of the communicating vessels running on the placental surface towards the umbilicus of the acardiac twin. At 20 weeks we performed endoscopic laser coagulation of the umbilical vessels of the acardiac twin. A sheath (9.8 Charriere) with a 1.9 mm diameter rigid fetoscope (field of vision 60 degrees) was introduced percutaneously under local anesthesia into the amniotic cavity of the "pump" twin. Under sonographic control the fetoscope was directed towards the communicating vessels on the placental surface. A Nd-YAG laser (0.4 mm diameter fiber) was used to coagulate two vessels, artery and vein, until interruption of the reversed arterial perfusion was accomplished. Tricuspid regurgitation of the normal twin disappeared throughout the following two weeks and no further complications occurred throughout pregnancy. At 39 weeks a healthy girl was delivered vaginally. No at the age of 3 months she is developing normally. Minimal invasive endoscopic laser coagulation of the umbilical vessels of the acardiac twin appears to be the optimal currently available treatment for the normal twin, for which otherwise a high mortality ( > 50%) and morbidity must be expected.
我们报告了一例成功进行宫内手术治疗的无心畸胎双胎妊娠病例。妊娠18周时,患者出现羊水过多及无头无心的水肿型无心畸胎,供血双胎出现充血性心力衰竭迹象。彩色多普勒超声可定位胎盘表面朝向无心畸胎脐部走行的交通血管。20周时,我们对无心畸胎的脐血管进行了内镜激光凝固术。在局部麻醉下,经皮将一个直径9.8法式(9.8 Charriere)、带有直径1.9毫米硬性胎儿镜(视野60度)的鞘管插入“泵血”双胎的羊膜腔。在超声引导下,将胎儿镜对准胎盘表面的交通血管。使用钕钇铝石榴石激光(直径0.4毫米光纤)凝固两条血管,即动脉和静脉,直至反向动脉灌注中断。在接下来的两周内,正常双胎的三尖瓣反流消失,整个孕期未再出现其他并发症。39周时,经阴道分娩出一名健康女婴。3个月大时,她发育正常。对无心畸胎的脐血管进行微创内镜激光凝固术似乎是目前对正常双胎的最佳治疗方法,否则正常双胎预期会有较高的死亡率(>50%)和发病率。