[Evaluation of the efficacy of levamisole in corticosteroid-dependent nephrotic syndrome in children].

The efficacy of levamisole was evaluated in 22 steroid-dependent nephrotic children. All of them were treated before with glucocorticoids. In 45.5% of children, prednisone was with-drawn after levamisole treatment and the remissions obtained lasted more than six months, 18.2% of the children relapsed after prednisone withdrawal and 36.4% children did not respond to levamisole treatment. Levamisole could be recommended for steroid-dependent patients with recurrent infections, in which alkylating agents are contraindicated.