Christakis N A, Escarce J J
Department of Medicine, University of Chicago, IL 60637, USA.
N Engl J Med. 1996 Jul 18;335(3):172-8. doi: 10.1056/NEJM199607183350306.
Each year more than 220,000 Medicare beneficiaries receive care from hospice programs designed to enhance the quality of the end of life. Enrollment requires certification by a physician that the patient has a life expectancy of less than six months. We examined how long before death patients enrolled in hospice programs.
Using 1990 Medicare claim data, we analyzed the characteristics and survival of 6451 hospice patients followed for a minimum of 27 months with respect to mortality.
The patients' mean age was 76.4 years; 92.4 percent were white. Half the patients were women, and 80.2 percent had cancer of some type. The most common diagnoses were lung cancer (21.4 percent), colorectal cancer (10.5 percent), and prostate cancer (7.4 percent). The median survival after enrollment was only 36 days, and 15.6 percent of the patients died within 7 days. At the other extreme, 14.9 percent of the patients lived longer than six months. Survival varied substantially according to diagnosis, even after adjustment for age and co-existing conditions. The unadjusted survival after enrollment was shortest for those with renal failure, those with leukemia or lymphoma, and those with liver or biliary cancer; it was longest for those with chronic lung disease, those with dementia, and those with breast cancer. Patients at for-profit, larger, outpatient, or newer hospices lived longer after enrollment than those in other types of hospice programs.
Most patients who enter hospice care do so late in the course of their terminal illnesses. The timing of enrollment in hospice programs varies substantially with the characteristics of the patients and the hospices.
每年有超过22万名医疗保险受益人接受临终关怀项目的护理,这些项目旨在提高生命末期的质量。入院需要医生证明患者预期寿命少于6个月。我们研究了患者在临终关怀项目登记前还能活多久。
利用1990年医疗保险索赔数据,我们分析了6451名临终关怀患者的特征和生存情况,这些患者至少随访了27个月以观察死亡率。
患者的平均年龄为76.4岁;92.4%为白人。一半患者为女性,80.2%患有某种类型的癌症。最常见的诊断是肺癌(21.4%)、结直肠癌(10.5%)和前列腺癌(7.4%)。登记后的中位生存期仅为36天,15.6%的患者在7天内死亡。在另一个极端,14.9%的患者存活超过6个月。即使在调整年龄和并存疾病后,生存期也因诊断不同而有很大差异。登记后未经调整的生存期,肾衰竭患者、白血病或淋巴瘤患者以及肝癌或胆管癌患者最短;慢性肺病患者、痴呆患者和乳腺癌患者最长。营利性、规模较大、门诊或较新的临终关怀机构的患者登记后存活时间比其他类型临终关怀项目的患者长。
大多数进入临终关怀护理的患者在其晚期疾病过程中较晚才这样做。临终关怀项目的登记时间因患者和临终关怀机构的特征而有很大差异。