Pilecki O, Wysocki M, Swiatkiewicz V, Kołtan A, Kołtan S, Kurylak A, Kurylak D
Katedra i Klinika Chorób Dzieci Akademii Medycznej w Bydgoszczy.
Pediatr Pol. 1995 Mar;70(3):213-8.
A safe and effective method of venous access is important in the care and treatment of patients with malignancies. Thirty-seven Broviac-Hickman catheters were inserted in 32 children with haematological neoplastic disease. The mean indwelling time of the catheters was 7014 days. The catheters were used to administer chemotherapy and other drugs, blood products, and as well as to draw blood. Fever occurred 96 times. Forty-three percent of fever episodes were related to clinically documented infections and in 15% of cases, to catheter-related bacteremia caused by Gram-positive and Gram-negative strains in equivalent proportions. Fever was observed with a two fold greater incidence in patients with severe granulocytopenia (< 0.5 G/l).
一种安全有效的静脉通路建立方法对于恶性肿瘤患者的护理和治疗至关重要。32例血液系统肿瘤患儿共插入了37根Broviac-Hickman导管。导管的平均留置时间为7014天。这些导管用于输注化疗药物和其他药物、血液制品以及抽血。共发生发热96次。43%的发热事件与临床记录的感染有关，15%的病例与导管相关菌血症有关，革兰氏阳性菌和革兰氏阴性菌引起的菌血症比例相当。严重粒细胞减少（<0.5 G/l）的患者发热发生率高出两倍。
