Suzuki T, Obara Y, Sato Y, Saito G, Ichiwata T, Uchiyama T
Department of Ophthalmology, Dokkyo University School of Medicine, Koshigaya Hospital, Saitama, Japan.
Am J Ophthalmol. 1996 Jul;122(1):125-7. doi: 10.1016/s0002-9394(14)71979-8.
To treat a 63-year-old woman who experienced fairly rapid vision loss in association with small-cell carcinoma of the lung.
She underwent a full ophthalmologic examination, including fluorescein angiography and an immunologic study by Western blot analysis.
Fluorescein angiography demonstrated diffuse staining of the retinal vessels. She had 62-kd antiretinal antibody in her serum. Cancer-associated retinopathy was diagnosed.
The staining seen on the angiogram appears to indicate vasculitis, which would cause the characteristic attenuation of retinal vessels in this disease.