来自曼彻斯特一例皮肤白喉病例的产毒素轻型白喉棒状杆菌的流行病学及分子特征分析

Epidemiology and molecular characterisation of toxigenic Corynebacterium diphtheriae var mitis from a case of cutaneous diphtheria in Manchester.

作者信息

Hamour A A, Efstratiou A, Neill R, Dunbar E M

机构信息

Regional Department of Infectious Diseases and Tropical Medicine, University of Manchester, North Manchester General Hospital, Crumpsall, U.K.

出版信息

J Infect. 1995 Sep;31(2):153-7. doi: 10.1016/s0163-4453(95)92260-1.

DOI:10.1016/s0163-4453(95)92260-1

PMID:8666848

Abstract

Diphtheria is now an uncommon disease in Britain. We describe an imported case of cutaneous diphtheria in a previously immunised adult cause by C. diphtheriae var mitis. The control measures adopted to deal with the index case and two secondary cases so as to limit further spread among household and school contacts are outlined. Molecular typing was used to study the mode of spread of the organism among contacts.

摘要

白喉在英国如今已属罕见疾病。我们描述了一例输入性皮肤白喉病例，患者为一名既往已接种疫苗的成年人，由轻型白喉棒状杆菌引起。概述了为处理首例病例及两例二代病例所采取的控制措施，以限制在家庭和学校接触者中进一步传播。采用分子分型研究该病菌在接触者中的传播方式。