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先天性心脏病地中海贫血患者的骨髓移植

Bone marrow transplantation in a thalassemia patient with congenital heart disease.

作者信息

Baronciani D, Angelucci E, Agostinelli F, Mariotti E, Baldassarri M, Martinelli F, Lacerra G, Lucarelli G

机构信息

Divisione Ematologica e Centro Trapianto Midollo Osseo di Muraglia, Italy.

出版信息

Bone Marrow Transplant. 1996 Jan;17(1):119-20.

PMID:8673044
Abstract

We report a thalassemia patient suffering from congenital transposition of the great arteries, surgically corrected according to Mustard technique at the age of 4 months, who underwent bone marrow transplantation. Despite a syncopal episode occurring during the first day after marrow infusion the transplant was successful. Thirty-two months later, normalization of hematologic parameters was observed together with a substantial improvement in cardiac function.

摘要

我们报告了一名患有大动脉先天性转位的地中海贫血患者,该患者在4个月大时根据Mustard技术进行了手术矫正,并接受了骨髓移植。尽管在骨髓输注后的第一天出现了晕厥发作,但移植还是成功了。32个月后,血液学参数恢复正常,心脏功能也有了显著改善。

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