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环氧乙烷暴露的医学监测:马萨诸塞州医院的实践与临床发现

Medical surveillance for ethylene oxide exposure: practices and clinical findings in Massachusetts hospitals.

作者信息

LaMontagne A D, Mangione T W, Christiani D C, Kelsey K T

机构信息

Occupational Health Program, Harvard School of Public Health, Boston, Massachusetts 02115-9957, USA.

出版信息

J Occup Environ Med. 1996 Feb;38(2):144-54. doi: 10.1097/00043764-199602000-00012.

Abstract

The medical surveillance requirements of the Occupational Safety and Health Administration's (OSHA) ethylene oxide (EtO) standard became effective in 1985. However, little is known about the nature of the response of EtO users to this regulatory requirement. In an effort to begin to understand this, we conducted a survey of EtO health and safety in Massachusetts hospitals (n = 92). We determined the cumulative incidence of provision of EtO medical surveillance, the characteristics of the surveillance interventions provided, and the clinical findings of EtO medical surveillance efforts in Massachusetts hospitals. From 1985 to 1993, medical surveillance for EtO exposure was provided one or more times in 62% of EtO-using hospitals. Sixty-five percent of EtO medical surveillance providers reported performance of all five medical surveillance procedures required by OSHA's EtO standard. Medical surveillance provider certification in occupational medicine or nursing, and a greater extent of coverage of written medical surveillance policies, were related to higher likelihoods of fulfillment of OSHA-required procedures. Twenty-seven percent of medical surveillance providers reported detection of EtO-related symptoms or conditions, ranging from mucous membrane irritation to peripheral neuropathy. These findings reveal wide-spread implementation of OSHA-mandated EtO medical surveillance, with concomitant incomplete fulfillment of OSHA-specified procedures. From the provider-based survey, we estimate that one or more workers at 19% of EtO-using Massachusetts hospitals have experienced EtO-related health effects.

摘要

美国职业安全与健康管理局(OSHA)的环氧乙烷(EtO)标准中的医学监测要求于1985年生效。然而,对于环氧乙烷使用者对这一监管要求的反应性质,人们知之甚少。为了开始了解这一点,我们对马萨诸塞州的医院(n = 92)进行了一项环氧乙烷健康与安全调查。我们确定了提供环氧乙烷医学监测的累积发生率、所提供监测干预措施的特征,以及马萨诸塞州医院环氧乙烷医学监测工作的临床结果。1985年至1993年期间,62%的使用环氧乙烷的医院提供了一次或多次环氧乙烷暴露医学监测。65%的环氧乙烷医学监测提供者报告称执行了OSHA的环氧乙烷标准要求的所有五项医学监测程序。职业医学或护理方面的医学监测提供者认证,以及书面医学监测政策的更大覆盖范围,与更高可能性地完成OSHA要求的程序相关。27%的医学监测提供者报告检测到与环氧乙烷相关的症状或病症,范围从粘膜刺激到周围神经病变。这些发现揭示了OSHA强制要求的环氧乙烷医学监测的广泛实施,同时也存在未完全履行OSHA规定程序的情况。根据基于提供者的调查,我们估计在马萨诸塞州19%的使用环氧乙烷的医院中,有一名或多名工人经历了与环氧乙烷相关的健康影响。

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