Uccheddu A, Mattana A, Nardello O, Cagetti M
Università degli Studi, Cagliari, I Cattedra di Chirurgia Generale, Istituto di Chirurgia.
Minerva Chir. 1996 Jan-Feb;51(1-2):17-24.
Gastric cancer is a typical disease of old age, in fact about one half of the patients affect by it are aged over 65. Elderly patients imply a problematical choice of surgical treatment due to the general and specific risk and to life expectancy. In order to evaluate the specific features of gastric cancer in aged people and to share their experience in choosing the surgical treatment, a series of 50 patients with gastric cancer selected on the age > or = 75 years and observed from 1970 to 1993, was reviewed by the authors. Some features have been settled such as sex ratio approaching the unity, a prevalence of tumors located in the distal third of the stomach, the higher incidence of intestinal type and a wide incidence of intestinal type and a wide incidence of patients in III or IV stage. No surgical procedure was undertaken in eleven patients. The remaining 39 patients (78%) underwent a surgical procedure. In 22 patients (56.4) a resection was performed: 17 (77.3%) underwent a subtotal gastric resection, 11 curative and 6 palliative, and 5 (22.7%) a total gastrectomy out of necessity for tumor localization. In 17 patients (43.6%) a bypass procedure was carried out, while in 7 (17.9%) the surgical procedure was a simple laparatomy. Postoperative morbidity incidence was 17.9%, mortality rate 10.2%. Actuarial 5 years survival rate for curative resection was 41.5%. Median survival time was 13 months for patients who underwent a palliative resection and 6 months after bypass procedures. The data suggest that subtotal gastrectomy, also as palliative procedure, fits better to geriatric patients' requirements and is able to offer a satisfactory quality of life, to prevent cancer complications and to determine a longer survival.
胃癌是一种典型的老年疾病,实际上,受其影响的患者约有一半年龄超过65岁。由于存在一般风险和特殊风险以及预期寿命问题,老年患者的手术治疗选择存在问题。为了评估老年胃癌患者的具体特征并分享他们在选择手术治疗方面的经验,作者回顾了1970年至1993年间选取的50例年龄≥75岁的胃癌患者。已确定了一些特征,如性别比接近1,肿瘤多位于胃远端三分之一处,肠型发生率较高,Ⅲ期或Ⅳ期患者发生率较高。11例患者未进行手术。其余39例患者(78%)接受了手术。22例患者(56.4%)进行了切除手术:17例(77.3%)接受了胃次全切除术,其中11例为根治性切除,6例为姑息性切除,5例(22.7%)因肿瘤位置需要进行了全胃切除术。17例患者(43.6%)进行了旁路手术,7例(17.9%)的手术为单纯剖腹术。术后发病率为17.9%,死亡率为10.2%。根治性切除的5年精算生存率为41.5%。接受姑息性切除的患者中位生存时间为13个月,旁路手术后为6个月。数据表明,胃次全切除术,即使作为姑息性手术,也更符合老年患者的需求,能够提供令人满意的生活质量,预防癌症并发症,并延长生存期。