Dirik E, Sen A, Anal O, Cevik N T
Department of Pediatric Neurology, Dokuz Eylül University Medical Faculty, Izmir, Turkey.
Acta Paediatr Jpn. 1996 Apr;38(2):118-20.
Postictal serum prolactin and cortisol levels were measured in 37 children having either epilepsy, febrile seizure or syncopal attack and in 37 normal controls. Blood samples were obtained within 1.5 h following the seizure episode. All serum levels were compared between each group and the control groups. Significantly higher (P < 0.005) prolactin levels (56.64 +/- 34.78 ng/mL) were found in the epileptic group, compared to the levels in children with febrile seizures (21.72 +/- 12.92 ng/mL), syncope attacks (13.88 +/- 5.27 ng/mL) and the control group (14.32 +/- 5.05 ng/mL). In contrast, serum cortisol levels were non-specifically elevated in children with epilepsy, febrile seizures and syncopal attacks. Cortisol secretion appears to be non-specifically elevated in all stressful events. Elevated prolactin levels may be helpful in differentiating epilepsy from febrile seizures and syncope.
对37名患有癫痫、热性惊厥或晕厥发作的儿童以及37名正常对照者测定了发作后血清催乳素和皮质醇水平。在发作事件后的1.5小时内采集血样。比较了每组与对照组之间的所有血清水平。癫痫组的催乳素水平（56.64±34.78 ng/mL）显著高于热性惊厥儿童（21.72±12.92 ng/mL）、晕厥发作儿童（13.88±5.27 ng/mL）和对照组（14.32±5.05 ng/mL）（P<0.005）。相比之下，癫痫、热性惊厥和晕厥发作儿童的血清皮质醇水平非特异性升高。在所有应激事件中，皮质醇分泌似乎均非特异性升高。催乳素水平升高可能有助于鉴别癫痫与热性惊厥和晕厥。
