赞比亚孕妇中的乙型肝炎病毒感染情况。

Hepatitis B virus infection among pregnant women in Zambia.

作者信息

Oshitani H, Kasolo F, Tembo C, Mpabalwani M, Mizuta K, Luo N, Suzuki H, Numazaki Y

机构信息

Virus Research Center, Sendal National Hospital, Japan.

出版信息

East Afr Med J. 1995 Dec;72(12):813-5.

PMID:8689985

Abstract

The prevalence of hepatitis B virus (HBV) markers was studied in pregnant women attending antenatal clinics in Zambia. A total of 2,098 pregnant women were recruited into the study at three urban health centres in Lusaka, the capital city and four district hospitals in rural areas of different provinces of Zambia. The overall prevalence of HBsAg was 6.5% (137/2,098), and HBeAg was present in 16.1% (22/137) of those positive for HBsAg. Antibody positive rate (HBsAb and/or HBcAb) was 51.3% in randomly selected HBsAg negative samples. HBsAg positive rate varied between 3.3% and 13.6% in each study sites. Prevalence for both HBsAg and antibodies to HBV were significantly higher in rural areas (district hospitals) than in urban areas (urban health centres in Lusaka). These data show that although HBV is endemic in Zambia, the prevalence varies from region to region.

摘要

在赞比亚产前诊所就诊的孕妇中，对乙肝病毒（HBV）标志物的流行情况进行了研究。在赞比亚首都卢萨卡的三个城市医疗中心以及赞比亚不同省份农村地区的四家区级医院，共招募了2098名孕妇参与该研究。HBsAg的总体流行率为6.5%（137/2098），在HBsAg阳性者中，HBeAg的阳性率为16.1%（22/137）。在随机选取的HBsAg阴性样本中，抗体阳性率（HBsAb和/或HBcAb）为51.3%。每个研究地点的HBsAg阳性率在3.3%至13.6%之间。农村地区（区级医院）的HBsAg和HBV抗体流行率均显著高于城市地区（卢萨卡的城市医疗中心）。这些数据表明，尽管HBV在赞比亚呈地方性流行，但流行率因地区而异。