Leisewitz A L, Guthrie A J, Berry W
Department of Medicine, Faculty of Veterinary Science, University of Pretoria, Onderstepoort, Republic of South Africa.
J S Afr Vet Assoc. 1995 Dec;66(4):213-8.
The blood-gas, acid-base, and arterial oxygen status of 6 healthy blood donor dogs was studied at an altitude of 1250 metres on 2 occasions 3 days apart. The values, and repeatability, of a number of derived variables that describe oxygen status, including oxygen extraction tension (Px), extractable oxygen concentration (Cx), and oxygen compensation factor (Qx) were established in clinically healthy dogs. The Oxygen Status Algorithm computer programme which was developed for use in humans was used to calculate these derived variables. 2,3-Bisphosphoglycerate concentrations were measured spectrophotometrically and compared with 2,3-bisphosphoglycerate concentrations calculated by the Oxygen Status Algorithm. This study revealed that there were no significant differences between the means of any of the variables used to describe oxygen status on the two occasions. The mean Px of 38.74 mmHg, Cx of 4.38 ml/dl, and Qx of 1.2 were similar to those reported for man.
对6只健康供血犬在海拔1250米处进行了两次血气、酸碱及动脉血氧状态研究,两次研究间隔3天。在临床健康的犬中确定了一些描述氧状态的衍生变量的值及其重复性,这些变量包括氧摄取张力(Px)、可提取氧浓度(Cx)和氧补偿因子(Qx)。使用为人类开发的氧状态算法计算机程序来计算这些衍生变量。采用分光光度法测量2,3-二磷酸甘油酸浓度,并与通过氧状态算法计算出的2,3-二磷酸甘油酸浓度进行比较。该研究表明,两次研究中用于描述氧状态的任何变量的均值之间均无显著差异。平均Px为38.74 mmHg,Cx为4.38 ml/dl,Qx为1.2,与人类报告的数值相似。