Mathew B C, Augusti K T
Department of Biochemistry, University of Kerala, Thiruvananthapuram, India.
Indian J Exp Biol. 1996 Apr;34(4):346-50.
Garlic protein diet or daily administration of garlic oil to 2% cholesterol fed rats controlled significantly the increases in sulphated glycosaminoglycans in their heart and aorta. However hyaluronic acid level increased. UDPG dehydrogenase decreased and several degrading enzymes increased in the aorta on treatment. The effects of treatment were just the reverse in liver. The high percentage of cysteine in garlic protein and the reactive disulphide group in the oil may be responsible for their beneficial effects.
给喂食2%胆固醇的大鼠采用大蒜蛋白饮食或每日给予大蒜油，可显著控制其心脏和主动脉中硫酸化糖胺聚糖的增加。然而，透明质酸水平升高。治疗后，主动脉中UDPG脱氢酶减少，几种降解酶增加。在肝脏中，治疗效果则相反。大蒜蛋白中高比例的半胱氨酸和大蒜油中的活性二硫基团可能是其产生有益效果的原因。
