Prayson R A
Department of Anatomic Pathology, Cleveland Clinic Foundation, Ohio, USA.
Pathology. 1996 Jan;28(1):25-7. doi: 10.1080/00313029600169453.
Angiotropic large cell lymphoma is a rarely encountered disorder characterized by a proliferation of malignant lymphoid cells within vascular lumina. Sites usually affected include the skin and central nervous system, although involvement of multiple other organ symptoms have been described including peripheral nerve and skeletal muscle. Simultaneous involvement of both skeletal muscle and peripheral nerve has rarely been reported. In most of those cases the diagnosis was made only at the time of autopsy. A case of an elderly male with angiotropic large cell lymphoma and in whom the diagnosis was made antemortem on a peripheral nerve and skeletal muscle biopsy is reported.
血管中心性大细胞淋巴瘤是一种罕见的疾病,其特征是恶性淋巴样细胞在血管腔内增殖。通常受累的部位包括皮肤和中枢神经系统,不过也有报道称可累及其他多个器官,包括周围神经和骨骼肌。同时累及骨骼肌和周围神经的情况鲜有报道。在大多数此类病例中,诊断仅在尸检时做出。本文报告了一例老年男性血管中心性大细胞淋巴瘤患者,其通过对周围神经和骨骼肌活检进行了生前诊断。