Kuroda M, Ojima H, Igarashi H, Murakami K, Okada A, Shinkai M
Department of Anatomy, Toho University School of Medicine, Japan.
Brain Res. 1996 Feb 5;708(1-2):185-90. doi: 10.1016/0006-8993(95)01438-1.
A combined study of anterograde axonal degeneration and Golgi electron microscopic technique was designed to examine the distribution and density of axon terminals from the mediodorsal thalamic nucleus (MD) over layer III pyramidal cells in the prelimbic cortex of the rat. The reconstructive analysis of serial ultrathin sections of gold-toned apical and basal dendrites of layer III pyramidal cells showed that degenerating thalamocortical axon terminals from MD formed asymmetrical synaptic contacts predominantly with dendritic spines of the identified basal dendrites as well as apical dendrites. There was little difference in the numerical density of thalamocortical synapses from MD per unit length of both apical and basal dendrites.
设计了一项关于顺行性轴突退变与高尔基电子显微镜技术的联合研究，以检查大鼠前边缘皮层中来自丘脑背内侧核（MD）的轴突终末在III层锥体细胞上的分布和密度。对III层锥体细胞的金色顶端和基底树突的连续超薄切片进行的重建分析表明，来自MD的退化丘脑皮质轴突终末主要与已识别的基底树突以及顶端树突的树突棘形成不对称突触联系。MD丘脑皮质突触在顶端和基底树突每单位长度上的数量密度几乎没有差异。
