Dawson K P, McIlvenny S, Quinn S, Harron D W
Faculty of Medicine & Health Sciences, UAE University, Al Ain, United Arab Emirates.
Fam Pract. 1996 Apr;13(2):179-81. doi: 10.1093/fampra/13.2.179.
Although we are uncertain of its therapeutic mechanism, paracetamol is seen as a safe drug, especially for children. However, adult fatalities from overdose and its association with hepatotoxicity have cast doubt on its safety.
We aimed to establish the prescribing patterns of paracetamol in the United Arab Emirates (UAE).
The prescribing patterns in the UAE for paracetamol were studied by obtaining information on national utilization and recording in detail the pattern of prescribing in one primary health care centre.
Paracetamol was included in 35.5% of all prescriptions from the study practice. Of these, 58.5% were for children under 12 years of age and overall 13.5% were for those infants under one year of age.
National prescribing utilization is in keeping with the prescribing patterns of the index practice. Paracetamol prescribing is reaching epidemic proportions and the potential dangers of hepatotoxicity and the inhibition of the immune response in children are discussed.
尽管我们不确定对乙酰氨基酚的治疗机制，但它被视为一种安全的药物，尤其是对儿童而言。然而，过量服用导致的成人死亡及其与肝毒性的关联，让人对其安全性产生了怀疑。
我们旨在确定阿拉伯联合酋长国（阿联酋）对乙酰氨基酚的处方模式。
通过获取全国用药信息并详细记录一个初级卫生保健中心的处方模式，对阿联酋对乙酰氨基酚的处方模式进行了研究。
研究机构开具的所有处方中，35.5%包含对乙酰氨基酚。其中，58.5%是给12岁以下儿童的，总体而言，13.5%是给一岁以下婴儿的。
全国处方用药情况与该研究机构的处方模式相符。对乙酰氨基酚的处方量已达到流行程度，并讨论了其对儿童肝毒性和免疫反应抑制的潜在危险。
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