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前庭诱发反应:平衡测量学的一个新前沿。

Vestibular evoked responses: a new frontier in equilibriometry.

作者信息

Claussen C F

机构信息

Neurootological Research Center, Bad Kissingen, Germany.

出版信息

Acta Otolaryngol Suppl. 1995;520 Pt 1:113-6. doi: 10.3109/00016489509125204.

Abstract

Modern neurootology has proved that many vertigo patients suffer from central dysequilibrium states. As vertigo patients are very frequent amongst our patient population we have to increase our diagnostic as well as therapeutical efforts. Since 1965, eliciting vestibular evoked cortical potentials has been possible. A method of evoked responses based upon computation of several stimulus responses has been used since then. Besides we are also using the frequency analysis of representative epochs of ongoing vestibular-ocular or retino-ocular reactions has been used since then. For diagnostic purposes we are combining various techniques like systematic history taking, ENG, ECG, CCG and BEAM. Brain electrical activity mapping (BEAM) is a newly developed tool, which we can also use for differentiating central from peripheral vestibular diseases. We are applying this technique for topographic correlates of vertigo related functional changes as well as for spatiotemporal analysis of cerebral evoked potentials due to vestibular stimulation. By means of a specific vestibular evoked potential technique, 6 typical cortical wave patterns can be elicited, which are displayed in the EEG curves as well as in colour maps of the whole scalp. The interactions between the various cortical structures are turning into an image similar to a weather map. BEAM, the fourth plan for projecting vertigo disorders, is now also bound into our concept for planning and monitoring a drug based therapy.

摘要

现代神经耳科学已证明,许多眩晕患者患有中枢性平衡失调状态。由于眩晕患者在我们的患者群体中非常常见,我们必须加大诊断和治疗力度。自1965年以来,诱发前庭诱发皮质电位已成为可能。从那时起,一种基于计算多个刺激反应的诱发反应方法就被使用了。此外,我们还一直在使用对正在进行的前庭眼动或视网膜眼动反应的代表性时段进行频率分析。为了诊断目的,我们将各种技术结合起来,如系统病史采集、眼震电图、心电图、计算机化动态测听和脑电地形图。脑电活动地形图(BEAM)是一种新开发的工具,我们也可以用它来区分中枢性和外周性前庭疾病。我们正在将这项技术应用于眩晕相关功能变化的地形学相关性研究,以及前庭刺激引起的脑诱发电位的时空分析。通过一种特定的前庭诱发电位技术,可以引出6种典型的皮质波型,它们显示在脑电图曲线上以及整个头皮的彩色图谱中。各种皮质结构之间的相互作用变成了一幅类似于气象图的图像。BEAM,即眩晕疾病的第四种投射方案,现在也被纳入我们基于药物治疗的规划和监测概念中。

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