Lumbar puncture in the clinical evaluation of children with seizures associated with fever.

This study was prospectively conducted to determine the frequency and yield of lumbar punctures performed in children with fever and seizures and to identify the criteria that were used by emergency physicians in selecting patients for this diagnostic procedure. During the five-year period from 1988 to 1992, 200 previously healthy children aged three months to five years were brought consecutively to the pediatric emergency department, after their seizure associated with fever. Lumbar puncture was performed in 51% of the cases and resulted in the detection of seven (3.5%) cases of meningitis, three (1.5%) of which were bacterial. An age less than 18 months, a febrile illness lasting over 48 hours, suspicious symptoms and signs of meningitis, and complex seizure features had significant influence on the decision of performing a lumbar puncture. Most children with meningitis had lethargy, irritability, and vomiting, and all had complex seizure features.