Bérardi-Grassias L, Kahla N, Richardin F, Boisivon A, Ghnassia J C, Holler C, Leneveu M, Martelli M, Rast G
Laboratoire de Bactériologie, Hôpital de Mantes, Mantes-la-Jolie, France.
Pathol Biol (Paris). 1996 May;44(5):411-5.
During 2 months (01.01.95-28.02.95), we noted for each Staphylococcus aureus (SA) isolates, identification and susceptibility methods, hospital size, medical speciality, source, penicillin (P) and methicillin (M) susceptibility. For each non repetitive methicillin resistant SA we noted phenotype of aminoglycoside resistance of SA to 6 antistaphylococci drugs. We isolated 399 SA, SAP sensitives 6.5%, methicillin resistant SA (MRSA) 31.8%. MRSA in acute care unit 28.4%, non acute care unit 61.7%, surgery 28.6%, medicine 36.5%, orthopedics 34.5%, pédiatrics 4%, ICU 38.8%, others 10.3%. MRSA from wound 28.2%, respiratory tract 38.3% blood 22.5%, urine 58.5%, others 25.8% - MRSA kanamycin 1.7%, kanamycin tobramycin 36.2%, kanamycin, tobramycin, gentamicin 56.9% - MRSA erythromycin 79.5%, pefloxacin 91.3%, rifampicin 53.5%, acide fusidique 8.7%, fosfomycine 18.9%, TMP SMZ 5.5%. The proportion MRSA is equivalent among medical specialities predominant in urine cultures and respiratory tract. It should be better to carry on the survey for more than two months in each hospital.
在2个月期间（1995年1月1日至1995年2月28日），我们记录了每株金黄色葡萄球菌（SA）的分离株、鉴定和药敏方法、医院规模、医学专科、来源、青霉素（P）和甲氧西林（M）敏感性。对于每株非重复性耐甲氧西林金黄色葡萄球菌，我们记录了其对6种抗葡萄球菌药物的氨基糖苷类耐药表型。我们分离出399株金黄色葡萄球菌，对苯唑西林敏感的占6.5%，耐甲氧西林金黄色葡萄球菌（MRSA）占31.8%。急性护理病房的MRSA占28.4%，非急性护理病房占61.7%，外科占28.6%，内科占36.5%，骨科占34.5%，儿科占4%，重症监护病房占38.8%，其他占10.3%。伤口来源的MRSA占28.2%，呼吸道占38.3%，血液占22.5%，尿液占58.5%，其他占25.8%。MRSA对卡那霉素耐药的占1.7%，对卡那霉素和妥布霉素耐药的占36.2%，对卡那霉素、妥布霉素和庆大霉素耐药的占56.9%。MRSA对红霉素耐药的占79.5%，对培氟沙星耐药的占91.3%，对利福平耐药的占53.5%，对夫西地酸耐药的占8.7%，对磷霉素耐药的占18.9%，对复方磺胺甲恶唑耐药的占5.5%。在以尿液培养和呼吸道为主的医学专科中，MRSA的比例相当。最好在每家医院进行超过两个月的调查。
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