Marjoram J, Strachan R, Allan A, Allan E
Hawthorns Surgery, Sutton Coldfield.
Br J Gen Pract. 1996 May;46(406):283-86.
A 2-year study was undertaken to determine the best way of setting up faecal occult blood screening for colorectal cancer in a single general practice in north Birmingham, a district with no pre-existing hospital-based screening programme for colorectal cancer. This programme was set up in close collaboration with the Departments of Surgery and Biochemistry at the local Good Hope Hospital Trust. This facilitated joint meetings between the staff of these hospital departments and the practice manager, who was responsible for organization of the study at the Hawthorns Surgery and also supervised the day-to-day running of the programme. Essentially, the study was organized and run by the practice manager and nurse.
The study was undertaken to prepare the way for other general practices in north Birmingham to screen selected populations for colorectal cancer.
A Haemoccult test kit was posted to patients together with an explanatory letter. The design of the screening programme was similar to the design of the 'screened arm' of the Medical Research Council (MRC) colorectal screening trial in Nottingham. On completion of the programme, questionnaires were posted to 100 responders and 100 non-responders to assess the level of patient acceptability for the screening study. A total of 3509 patients (1599 men and 1910 women) were invited to take part in the screening.
The response rate was 55.4%. Thirty-nine patients were referred from the screening study for further investigation. Colonoscopy identified nine adenomas in nine patients, and a further 12 patients were found to have colorectal carcinoma.
The findings from the study suggest that this method could be used as a model for other general practices introducing colorectal screening using Haemoccult.
在伯明翰北部的一家普通诊所开展了一项为期两年的研究，以确定在一个此前没有基于医院的结直肠癌筛查项目的地区，建立结直肠癌粪便潜血筛查的最佳方法。该项目是与当地古德霍普医院信托基金的外科和生物化学部门密切合作设立的。这促进了这些医院科室的工作人员与诊所经理之间的联席会议，诊所经理负责在山楂树外科组织这项研究，并监督该项目的日常运作。从本质上讲，这项研究是由诊所经理和护士组织并实施的。
开展这项研究是为了为伯明翰北部的其他普通诊所对特定人群进行结直肠癌筛查做好准备。
向患者邮寄了一份隐血检测试剂盒以及一封解释信。筛查项目的设计与诺丁汉医学研究理事会（MRC）结直肠癌筛查试验的“筛查组”设计类似。在项目结束后，向100名回应者和100名未回应者邮寄了问卷，以评估患者对筛查研究的接受程度。总共邀请了3509名患者（1599名男性和1910名女性）参与筛查。
回应率为55.4%。筛查研究中有39名患者被转诊进行进一步检查。结肠镜检查在9名患者中发现了9个腺瘤，另有12名患者被发现患有结直肠癌。
该研究结果表明，这种方法可以作为其他使用隐血检测进行结直肠癌筛查的普通诊所的一个模式。
