Rodríguez-Leal G A, Morán-Consuelos M A, Morán-Villota S
Departamento de Endoscopía Gastrointestinal, Instituto Nacional de la Nutrición Salvador Zubirán, Tialpan, México.
Gac Med Mex. 1995 Sep-Dec;131(5-6):505-12.
Acute suppurative cholangitis is a life-threatening condition and prompt biliary decompression (BD) is essential for survival. The evolution of thirty-one patients (21 women and 10 men, mean age 64 years) with acute suppurative cholangitis attended from February 1989 to February 1994 treated by endoscopic cannulation and sphincterotomy for biliary drainage were retrospectively reviewed. The mean hospital stay was 18 +/- 12 days and during hospitalization there were 5 deaths, none related to biliary drainage. Sixteen patients had previous cholecystectomy, 12 patients had previous cholangitis in the last year, 23 patients had choledocholithiasis and an additional three patients pancreatobiliary neoplasias and common duct stones. Only 67.7% showed the classic Charcot's triad (fever, abdominal pain and jaundice). Total bilirubin, aspartate aminotransferase, alanine aminotransferase and total leukocytes decreased significantly (p < 0.05) after BD. Retroperitoneal perforation was the only complication is a safe and effective procedure for emergency biliary decompression in the treatment of acute suppurative cholangitis.
急性化脓性胆管炎是一种危及生命的疾病,迅速进行胆道减压(BD)是生存的关键。回顾性分析了1989年2月至1994年2月期间收治的31例急性化脓性胆管炎患者(21例女性,10例男性,平均年龄64岁),这些患者接受了内镜插管和括约肌切开术进行胆道引流治疗。平均住院时间为18±12天,住院期间有5例死亡,均与胆道引流无关。16例患者曾行胆囊切除术,12例患者在过去一年曾患胆管炎,23例患者有胆总管结石,另外3例患者有胰胆管肿瘤和胆总管结石。只有67.7%的患者表现出典型的夏科氏三联征(发热、腹痛和黄疸)。BD后总胆红素、天冬氨酸转氨酶、丙氨酸转氨酶和白细胞总数显著下降(p<0.05)。腹膜后穿孔是唯一的并发症,是治疗急性化脓性胆管炎紧急胆道减压的一种安全有效的方法。