Yung A R, McGorry P D, McFarlane C A, Jackson H J, Patton G C, Rakkar A
Early Psychosis Prevention and Intervention Centre, Parkville, Victoria, Australia.
Schizophr Bull. 1996;22(2):283-303. doi: 10.1093/schbul/22.2.283.
This article describes the theoretical background, origins, and development of a new clinical service for intervention in the putatively prodromal phase of schizophrenia and other psychotic disorders. Establishing such a service required examination of conceptual issues such as the meaning of the prodrome in psychosis and its association with risk of subsequent psychosis, and of practical issues related to identifying prodromal patients in the community and engaging them in monitoring and treatment. Patients' needs, timing, and mode of treatment had to be considered. Preliminary data from the service's 20-month pilot phase are presented to help inform these issues.
本文描述了一项针对精神分裂症及其他精神障碍假定前驱期进行干预的新临床服务的理论背景、起源和发展。建立这样一项服务需要审视一些概念性问题,如精神病前驱期的含义及其与后续精神病风险的关联,以及与在社区中识别前驱期患者并促使他们接受监测和治疗相关的实际问题。必须考虑患者的需求、治疗时机和治疗方式。文中呈现了该服务20个月试点阶段的初步数据,以助于为这些问题提供信息。