Louaib D, François M, Coderc E, Dieu S, Nathanson M, Narcy P, Gaudelus J
Service de pédiatrie, hôpital Jean-Verdier, Bondy, France.
Arch Pediatr. 1996 Mar;3(3):254-7. doi: 10.1016/0929-693x(96)81304-2.
Dysplasias of the bony labyrinth are frequently associated with cerebrospinal fluid fistula and are usually discovered because of recurrent meningitis.
A 1 year-old infant was admitted for a pneumococcal meningitis which appeared 2 days after the occurrence of a clear otorrhea from the right ear. The same organism was isolated from the otorrhea fluid, which also contained cerebrospinal fluid as confirmed cytochemically. The meningitis rapidly resolved with antibiotic treatment. Auditory brain stem responses were abolished from the right ear. CT of the temporal bones showed a pseudo-Mondini type labyrinth dysplasia at the right ear and Mondini type dysplasia at the left one. A translabyrinthine cerebrospinal fluid fistula was discovered by surgical exploration of the right ear, occurring through a perforation in the stapedial foot plate. The leak was cured by packing the vestibule and obturating both oval and round windows. Three years after the operation, the child did not experience any further episode of otorrhea or meningitis.
Features suggesting a translabyrinthine fistula, especially otorrhea and deafness, should be systematically searched in any child with bacterial meningitis. Closure of these fistulas can prevent severe infectious recurrences.
骨迷路发育异常常与脑脊液瘘相关,通常因复发性脑膜炎而被发现。
一名1岁婴儿因肺炎球菌性脑膜炎入院,该脑膜炎在右耳出现清亮耳漏2天后发生。从耳漏液中分离出相同的病原体,经细胞化学证实耳漏液中也含有脑脊液。经抗生素治疗,脑膜炎迅速好转。右耳听觉脑干反应消失。颞骨CT显示右耳为假性蒙迪尼型迷路发育异常,左耳为蒙迪尼型发育异常。通过对右耳进行手术探查发现了经迷路的脑脊液瘘,瘘口位于镫骨底板穿孔处。通过填充前庭并封闭椭圆窗和圆窗治愈了漏液。术后三年,该儿童未再出现耳漏或脑膜炎发作。
对于任何患有细菌性脑膜炎的儿童,应系统检查提示经迷路瘘的特征,尤其是耳漏和耳聋。封闭这些瘘可预防严重感染复发。