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起源于硬脑膜凸面的颅内脑外神经母细胞瘤。

Intracranial extracerebral neuroblastoma originating from the convexity dura mater.

作者信息

Ishii N, Sawamura Y, Aoki T, Nagashima K, Kashiwaba T, Abe H

机构信息

Department of Neurosurgery, University of Hokkaido School of Medicine, Sapporo.

出版信息

Neurol Med Chir (Tokyo). 1996 Jan;36(1):19-22. doi: 10.2176/nmc.36.19.

Abstract

A 19-year-old female presented with an unusual intracranial extracerebral neuroblastoma originating from the dura mater. The tumor was located in the right frontal convexity, and had adhered neither to the underlining arachnoid membrane nor the cerebral cortex. The tumor feeders were meningeal arteries. Light microscopy showed the tumor consisted of small compact cells, forming numerous Homer-Wright rosettes. Immunohistochemical examination and electron micrography confirmed the diagnosis of neuroblastoma. Intracranial extracerebral neuroblastoma is extremely rare, especially originating from the dura mater. This neuroblastoma probably originated from heterotopic neuroglial nest cells in the meninges.

摘要

一名19岁女性患者,患有一例罕见的起源于硬脑膜的颅内脑外神经母细胞瘤。肿瘤位于右侧额部脑凸面,既未与下方的蛛网膜也未与大脑皮质粘连。肿瘤供血血管为脑膜动脉。光镜检查显示肿瘤由小而密集的细胞组成,形成大量霍纳-赖特菊形团。免疫组织化学检查和电子显微镜检查确诊为神经母细胞瘤。颅内脑外神经母细胞瘤极为罕见,尤其是起源于硬脑膜者。该神经母细胞瘤可能起源于脑膜中的异位神经胶质巢细胞。

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