原发性干燥综合征、溃疡性结肠炎与选择性IgA缺乏症。
Primary Sjögren's syndrome, ulcerative colitis and selective IgA deficiency.
作者信息
Steuer A, McCrea D J, Colaco C B
机构信息
Central Middlesex Hospital, London, UK.
出版信息
Postgrad Med J. 1996 Aug;72(850):499-500. doi: 10.1136/pgmj.72.850.499.
Abstract
A 24-year-old man with primary Sjögren's syndrome presented with xerophthalmia, xerostomia, and marked parotid swelling. He had a previous history of selective IgA deficiency and ulcerative colitis treated with sulphasalazine. Immunosuppression and withdrawal of sulphasalazine resulted in rapid resolution of the parotitis and disappearance of autoantibodies. A possible role for sulphasalazine in the induction of autoimmunity in this case is discussed.
摘要
一名24岁的原发性干燥综合征男性患者，出现了干眼症、口干症和腮腺明显肿大。他既往有选择性IgA缺乏症病史，曾用柳氮磺胺吡啶治疗溃疡性结肠炎。免疫抑制及停用柳氮磺胺吡啶后，腮腺炎迅速消退，自身抗体消失。本文讨论了柳氮磺胺吡啶在该病例自身免疫诱导中可能发挥的作用。
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