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[局部广泛软组织肉瘤的热放疗]

[Thermoradiotherapy in locally extensive soft tissue sarcoma].

作者信息

Goldobenko G V, Tkachev S I, Karapetian R M, Bokhian B I, Ivanov S I

出版信息

Vopr Onkol. 1996;42(3):67-71.

PMID:8801745
Abstract

The report discusses 138 cases of soft-tissue sarcoma: 92 patients initially received thermoradiotherapy, 46-radiotherapy. Local electromagnetic hyperthermia was found to potentiate the antitumor effect of ionizing radiation and to be followed by a significant increase in the frequency of complete and considerable regression of tumor, as compared with exposure to total doses of 30-32 Gy (66-70 Units). As a result, 5-year survival rate in cases of post-thermoradiotherapy conservative surgery rose to 54 +/- 5.2%, as compared with 26 +/- 6.8% after conservative surgery + radiotherapy. The percentage of patients who survived more than 5 years after conservative surgery + thermoradiotherapy or radiotherapy was 37 +/- 7 and 23 +/- 7.8, respectively.

摘要

该报告讨论了138例软组织肉瘤病例:92例患者最初接受了热放疗,46例接受了放疗。结果发现,与接受30 - 32 Gy(66 - 70单位)总剂量照射相比,局部电磁热疗可增强电离辐射的抗肿瘤效果,并使肿瘤完全和显著消退的频率显著增加。因此,热放疗后保守手术病例的5年生存率升至54±5.2%,而保守手术 + 放疗后的5年生存率为26±6.8%。保守手术 + 热放疗或放疗后存活超过5年的患者百分比分别为37±7和23±7.8。

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