Serum lidocaine concentrations after subcutaneous administration in patients undergoing cardiac catheterization in a pediatric institution.
作者信息
Cassidy S C, Jones P R, Cox S, Walson P D, Allen H D
机构信息
Department of Pediatrics, Ohio State University, Columbus, USA.
出版信息
J Pediatr. 1996 Sep;129(3):464-6. doi: 10.1016/s0022-3476(96)70085-9.
PMID:8804342
Abstract
OBJECTIVE
We wished to determine serum lidocaine concentrations after subcutaneous injection during cardiac catheterization.
METHOD
Serum lidocaine concentrations were measured in 50 patients during catheterization.
RESULTS
Serum concentration was linearly related to dose per kilogram of body weight. Lidocaine concentrations were therapeutic in 38% of patients.
CONCLUSION
Lidocaine dose must be considered when the drug is used for local anesthesia in children.
摘要
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