RNA作为蛋白质的功能性模拟物出现。
RNA surfaces as functional mimetics of proteins.
作者信息
Keene J D
机构信息
Department of Microbiology, Duke University Medical Center, Durham, NC 27710, USA.
出版信息
Chem Biol. 1996 Jul;3(7):505-13. doi: 10.1016/s1074-5521(96)90139-8.
PMID:8807880
Abstract
Accumulating evidence suggests that RNA molecules can form surfaces that mimic those of proteins. Reactivity of autoantibodies with RNA surfaces may be due to cross-reactivity between a protein epitope and the RNA. The structural mimicry detected by an autoantibody may reflect functional mimicry.
摘要
越来越多的证据表明，RNA分子可以形成与蛋白质表面类似的表面。自身抗体与RNA表面的反应性可能是由于蛋白质表位与RNA之间的交叉反应。自身抗体检测到的结构模拟可能反映功能模拟。
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