系统性红斑狼疮治疗期间发生的带状疱疹性脊髓炎。

Herpes zoster myelitis occurring during treatment for systemic lupus erythematosus.

作者信息

Ebo D G, DeClerck L S, Stevens W J, Ieven M, Ursi D, Van Goethem J W, Couttenye M M

机构信息

Department of Immunology, Allergology, and Rheumatology, University of Antwerp, Belgium.

出版信息

J Rheumatol. 1996 Mar;23(3):548-50.

PMID:8833001

Abstract

A woman with systemic lupus erythematosus (SLE) presented with a zoster eruption. Transverse myelitis developed at the site of the dermatomal distribution of the rash. SLE and varicella zoster virus (VZV) can both cause myelitis, and are difficult to differentiate. The topographic association between the cutaneous and the neurological involvement suggesting VZV myelitis was confirmed by polymerase chain reaction (PCR) for VZV in the cerebrospinal fluid. This case illustrates the potential role of the selective amplification of VZV DNA in cerebrospinal fluid to diagnose central neurological complications associated with VZV. The value of magnetic resonance imaging of the spinal cord in the evaluation of patients with myelitis is emphasized.

摘要

一名患有系统性红斑狼疮（SLE）的女性出现了带状疱疹皮疹。横贯性脊髓炎在皮疹的皮节分布部位发生。SLE和水痘带状疱疹病毒（VZV）均可引起脊髓炎，且难以鉴别。皮疹的皮肤受累与神经受累之间的部位关联提示VZV脊髓炎，这一点通过脑脊液中VZV的聚合酶链反应（PCR）得到了证实。该病例说明了脑脊液中VZV DNA的选择性扩增在诊断与VZV相关的中枢神经并发症方面的潜在作用。强调了脊髓磁共振成像在脊髓炎患者评估中的价值。