支气管细胞性神经鞘瘤

Cellular schwannoma of the bronchus.

作者信息

Nesbitt J C, Vega D M, Burke T, Mackay B

机构信息

Department of Thoracic and Cardiovascular Surgery, University of Texas M.D. Anderson Cancer Center, Houston 77030, USA.

出版信息

Ultrastruct Pathol. 1996 Jul-Aug;20(4):349-54. doi: 10.3109/01913129609016336.

DOI:10.3109/01913129609016336

PMID:8837342

Abstract

A cellular schwannoma in a bronchus of a 64-year-old female is reported with immunocytochemical and ultrastructural observations. One previous case arising in the lung has been reported. The tumor formed a 3-cm exophytic mass in a segmental bronchus. Pneumonectomy was performed. The tumor was moderately cellular and devoid of Verocay bodies, and the spindle cells were immunoreactive for S-100 protein. Electron microscopy revealed schwannian features that were less developed than in a classic schwannoma.

摘要

报道了一名64岁女性支气管内的细胞性神经鞘瘤，并进行了免疫细胞化学和超微结构观察。此前已有1例发生于肺部的病例报道。肿瘤在段支气管内形成一个3厘米的外生性肿块。实施了肺切除术。肿瘤细胞中度密集，无Verocay小体，梭形细胞对S-100蛋白呈免疫反应性。电子显微镜检查显示神经鞘瘤特征，但其发育程度低于经典神经鞘瘤。